SCTIMST Launches CASPRO & BONYX: innovative Drug-Eluting Bone Graft Products

Feb 2, 2025

Drug-Eluting Bone Grafts, Biomedical Innovation, Indian Medical Research
Drug-Eluting Bone Grafts, Biomedical Innovation, Indian Medical Research

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Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) has launched two revolutionary drug-eluting bone graft products, CASPRO and BONYX, to enable better bone healing and site-specific drug delivery. Developed by SCTIMST's Biomedical Technology Wing and commercialized by Onyx Medicals Pvt Ltd, Meerut, these next-generation biomaterials enable controlled release of drugs and improved bone regeneration.

Key Highlights:
BONYX:

  • Targeted drug delivery bioceramic beads for bone infections.

  • Enables vacuum loading of antibiotics or drugs in liquid form.

  • Controlled drug release for over 30 days at the site of implantation.

  • Osteoconductive in nature, enabling bone integration and regeneration.

CASPRO:

  • Self-setting mouldable bioactive bone cement.

  • Processed from synthetic medical-grade basanite (calcium sulfate hemihydrate) reinforced with phosphate ions.

  • Gel-like or paste-like in the moist state, ideal for bone defect repair.

  • Enables drug incorporation in powder or liquid form, releasing for over 21 days.


  • Decade-Long Research Effort:

The products underwent years of scientific development, proofing, and regulatory clearances according to international standards.

  • Academia-Industry Collaboration Model:

CASPRO & BONYX show a successful model for biomedical product innovation in India.

Statements from Leaders or Officials:
S. Kris Gopalakrishnan, President, SCTIMST:
“The launch of CASPRO and BONYX marks a significant achievement in biomedical technology. These innovations are the result of extensive research and collaboration, positioning India as a key player in global medical advancements.”Release of CASPRO and BONYX is anticipated to improve bone healing therapy, enable orthopedic applications, and enhance benefits to patients. Controlled delivery of drugs treats chronic bone infection, while their biocompatibility provides better integration with native bone. With coordinated academic and industry efforts, SCTIMST has created a viable model for production of globally relevant biomedical products.

Drug-Eluting Bone Grafts
Biomedical Innovation
Indian Medical Research
Drug-Eluting Bone Grafts
Biomedical Innovation
Indian Medical Research

SCTIMST Launches CASPRO & BONYX: innovative Drug-Eluting Bone Graft Products

Feb 2, 2025

Drug-Eluting Bone Grafts, Biomedical Innovation, Indian Medical Research
Drug-Eluting Bone Grafts, Biomedical Innovation, Indian Medical Research

Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) has launched two revolutionary drug-eluting bone graft products, CASPRO and BONYX, to enable better bone healing and site-specific drug delivery. Developed by SCTIMST's Biomedical Technology Wing and commercialized by Onyx Medicals Pvt Ltd, Meerut, these next-generation biomaterials enable controlled release of drugs and improved bone regeneration.

Key Highlights:
BONYX:

  • Targeted drug delivery bioceramic beads for bone infections.

  • Enables vacuum loading of antibiotics or drugs in liquid form.

  • Controlled drug release for over 30 days at the site of implantation.

  • Osteoconductive in nature, enabling bone integration and regeneration.

CASPRO:

  • Self-setting mouldable bioactive bone cement.

  • Processed from synthetic medical-grade basanite (calcium sulfate hemihydrate) reinforced with phosphate ions.

  • Gel-like or paste-like in the moist state, ideal for bone defect repair.

  • Enables drug incorporation in powder or liquid form, releasing for over 21 days.


  • Decade-Long Research Effort:

The products underwent years of scientific development, proofing, and regulatory clearances according to international standards.

  • Academia-Industry Collaboration Model:

CASPRO & BONYX show a successful model for biomedical product innovation in India.

Statements from Leaders or Officials:
S. Kris Gopalakrishnan, President, SCTIMST:
“The launch of CASPRO and BONYX marks a significant achievement in biomedical technology. These innovations are the result of extensive research and collaboration, positioning India as a key player in global medical advancements.”Release of CASPRO and BONYX is anticipated to improve bone healing therapy, enable orthopedic applications, and enhance benefits to patients. Controlled delivery of drugs treats chronic bone infection, while their biocompatibility provides better integration with native bone. With coordinated academic and industry efforts, SCTIMST has created a viable model for production of globally relevant biomedical products.

Share:

Drug-Eluting Bone Grafts
Biomedical Innovation
Indian Medical Research
Drug-Eluting Bone Grafts
Biomedical Innovation
Indian Medical Research