Researchers at the National Institute of Technology Karnataka (NITK), Surathkal, have successfully developed a novel biosensor capable of early-stage detection of dengue fever. The innovative diagnostic tool, created by Prof. Badekai Ramachandra Bhat from the Department of Chemistry and research scholar Shreeganesh Subraya Hegde, aims to significantly improve the timely diagnosis of dengue, a mosquito-borne viral disease that poses a major global health challenge.

Key Highlights:
Advanced Dengue Detection:

• The newly developed biosensor can identify dengue fever during its early stages, potentially enabling quicker and more effective medical interventions.

• Unlike existing enzyme-based detection tools that have limited shelf life, this biosensor leverages carbon-based materials with enhanced stability, ensuring longer shelf life and improved reliability.

Technology Behind the Biosensor:

• The biosensor uses biomass-derived, porous carbon materials which provide an unprecedented sensitivity level.

• Its unique electrochemical design allows the precise detection of even trace amounts of dengue virus at early stages of infection, greatly enhancing diagnostic accuracy and speed.

Real-world Validation and Practicality:
Successful validation through real sample analysis confirmed the biosensor’s effectiveness in practical scenarios, showcasing its significant potential for improving patient outcomes and supporting better disease management strategies globally.

Patent and Technology Transfer Readiness:

• The research team received an Indian patent in January 2025 after initiating the project in late 2023 and applying for the patent by mid-2024.

• The biosensor is now fully ready for technology transfer, facilitating large-scale production and deployment.

Statements from Researchers:

• Prof. Badekai Ramachandra Bhat, Department of Chemistry, NITK:

“Our diagnostic tool offers a revolutionary improvement over traditional methods by providing an unprecedented sensitivity level, reliable detection, and extended shelf life. This could significantly enhance early intervention and patient management for dengue fever worldwide.”

• Shreeganesh Subraya Hegde, Research Scholar, NITK:

“The biosensor's design ensures precision and cost-effectiveness, allowing even resource-limited settings to effectively tackle rising dengue cases with timely diagnosis.”The innovative biosensor by NITK researchers represents a significant advancement in the global fight against dengue. As dengue cases continue to rise, this technology holds immense promise for large-scale implementation in affected regions, providing quicker diagnosis and better treatment outcomes.